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Malegra 100 belongs to a group of medicaments known as PDE5 inhibitors. To learn exactly how the medicine works, it is essential to explain the physiological mechanism of erection. After the s**ual arousal, nitrogen oxide is discharged in the hollow corpus body of the p*nis. After releasing Nitrogen oxide actives, the enzyme called guanylate cyclase leading to the synthesis of cyclic GMP or cGMP.